INTRANET

Clément Mettling

Research Scientist

I have acquired a background in molecular biology by working on various topics including neurodegenerative diseases and AIDS. My current project in the human evolutionary biology team focuses on adaptation to risk. We have recently shown a genetic selection of the dopamine receptor DRD4 in a volcanic area. We would like to confirm this result in other volcanoes, and conduct a genomic study to characterize other loci involved in risk taking.

 

39 documents

  • Yanti Ariyanti, Sarah Nila, Winati Nurhayu, Dimitri Dubois, Kanthi Arum Widayati, et al.. Perceptual Advantages of People Living in Semeru Volcanic Areas, Indonesia: An MRCV (Multiple Response Categorical Variable) Analysis. HAYATI Journal of Biosciences, 2026, 33 (3), pp.739-749. ⟨10.4308/hjb.33.3.739-749⟩. ⟨hal-05492915⟩
  • Mehwish Younas, Sandrine Gimenez, Yea-Lih Lin, Clément Mettling, Domenico Maiorano, et al.. γ-Aminobutyric Acid-Induced Monocytic Reactive Oxygen Species Impair CD4 Restoration in Treated Adults With HIV-1. Journal of Infectious Diseases, In press, pp.jiaf058. ⟨10.1093/infdis/jiaf058⟩. ⟨hal-05057438⟩
  • Adeline Guigues, Sandrine Gimenez, Clément Mettling, Damien Maurel, Etienne Doumazane, et al.. The EBI2 receptor is coexpressed with CCR5 in CD4+ T cells and boosts HIV-1 R5 replication. AIDS. Official journal of the international AIDS Society, 2024, 38 (10), pp.1449-1459. ⟨10.1097/QAD.0000000000003931⟩. ⟨hal-04748558⟩
  • Hervé Técher, Diyavarshini Gopaul, Jonathan Heuzé, Nail Bouzalmad, Baptiste Leray, et al.. MRE11 and TREX1 control senescence by coordinating replication stress and interferon signaling. Nature Communications, 2024, 15 (1), pp.5423. ⟨10.1038/s41467-024-49740-w⟩. ⟨hal-04748159⟩
  • Lucy Kundura, Renaud Cezar, Emma Ballongue, Sonia André, Moïse Michel, et al.. Low Percentage of Perforin-Expressing NK Cells during Severe SARS-CoV-2 Infection: Consumption Rather than Primary Deficiency. Journal of Immunology, 2024, 212 (7), pp.1105 - 1112. ⟨10.4049/jimmunol.2300359⟩. ⟨hal-04748173⟩
  • Hervé Técher, Diyavarshini Gopaul, Jonathan Heuzé, Baptiste Leray, Audrey Vernet, et al.. Regulation of oncogene-induced senescence by the MRE11 and TREX1 nucleases. 2023. ⟨hal-04315770⟩
  • Malvina Schatz, Laetitia Marty, Camille Ounadjela, Phuoc Bao Viet Tong, Ilaria Cardace, et al.. A Tripartite Complex HIV-1 Tat-Cyclophilin A-Capsid Protein Enables Tat Encapsidation That Is Required for HIV-1 Infectivity. Journal of Virology, 2023, 97 (4), ⟨10.1128/jvi.00278-23⟩. ⟨hal-04106774⟩
  • Gwen-Jirō Clochard, Aby Mbengue, Clément Mettling, Birane Diouf, Charlotte Faurie, et al.. The effect of the 7R allele at the DRD4 locus on risk tolerance is independent of background risk in Senegalese fishermen. Scientific Reports, 2023, 13 (1), pp.622. ⟨10.1038/s41598-022-27002-3⟩. ⟨hal-03954770⟩
  • Lucy Kundura, Sandrine Gimenez, Renaud Cezar, Sonia André, Mehwish Younas, et al.. Angiotensin II induces reactive oxygen species, DNA damage, and T-cell apoptosis in severe COVID-19. Journal of Allergy and Clinical Immunology, 2022, 150 (3), pp.594-603.e2. ⟨10.1016/j.jaci.2022.06.020⟩. ⟨hal-03837641⟩
  • Vo-Minh-Hoang Bui, Clément Mettling, Jonathan Jou, H Sunny Sun. Genomic amplification of chromosome 20q13.33 is the early biomarker for the development of sporadic colorectal carcinoma. BMC Medical Genomics, 2020, 13, ⟨10.1186/s12920-020-00776-z⟩. ⟨hal-03078496⟩

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Clément Mettling

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